A group of membrane proteins can be extracted from membranes only by using detergents. All the proteins in this group have a similar amino acid sequence at their C-terminus: -KKKKKXXC (where K stands for lysine, X stands for any amino acid, and C stands for cysteine). This sequence is essential for their attachment to the membrane. What is the most likely way in which the C-terminal sequence attaches these proteins to the membrane?
(a) The cysteine residue is covalently attached to a membrane lipid.
(b) The peptide spans the membrane as an a helix.
(c) The peptide spans the membrane as part of a ß sheet.
(d) The positively charged lysine residues interact with an acidic integral membrane protein.
Answer:
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